The Fernald Community Cohort: Lessons Learned from Developing a Large Epidemiology Cohort with a 25 Year Heritage

Members of the Fernald Community Cohort (FCC, N=9782) received medical screenings from 1990-2008 (18 years). Although eligibility for the medical monitoring program was based on living within 5 miles of a uranium refinery, exposure studies conducted by CDC demonstrated that much of the cohort never experienced uranium exposure beyond usual background levels, and thus there are both uranium-exposed and non-exposed persons in the cohort. Cohort follow-up continues to the present. Members of this multi-generational cohort completed yearly questionnaires (total 96,091) on a wide array of health risk factors and received a comprehensive medical examination every 2 or 3 years (total 43,283) including clinical laboratory tests, mammograms, PFTs, EKGs, and chest x-rays.

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