Influence of Socioeconomic Status on the Whole Blood Transcriptome in African Americans

The correlation between low socioeconomic status (SES) and poor health outcome or higher risk of disease has been consistently reported by many epidemiological studies across various race/ancestry groups. It is postulated that social factors play an important etiologic role in the racial disparities in health observed in African-Americans. However, the biological mechanisms linking low SES to disease and/or disease risk factors are not well understood and remain relatively under-studied. The analysis of the blood transcriptome is a promising window for elucidating how social and environmental factors influence the molecular networks governing health and disease.

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