Combined use of apatinib mesylate and vinorelbine versus vinorelbine alone in recurrent or metastatic triple-negative breast cancer: study protocol for a randomized controlled clinical trial. Trials. 2020 May 24;21(1):420 Authors: Wu S, Zhang L, Li H, Xu J, Jiang C, Sun T Abstract BACKGROUND: The emergence of new molecular targeted drugs provides new prospects for the treatment of advanced breast cancer; the future therapeutic trend includes chemotherapy...
Tue May 26, 2020 14:19
Symphony of epigenetic and metabolic regulation-interaction between the histone methyltransferase EZH2 and metabolism of tumor. Clin Epigenetics. 2020 May 24;12(1):72 Authors: Zhang T, Gong Y, Meng H, Li C, Xue L Abstract Increasing evidence has suggested that epigenetic and metabolic alterations in cancer cells are highly intertwined. As the master epigenetic regulator, enhancer of zeste homolog 2 (EZH2) suppresses gene transcription mainly by catalyzing...
Tue May 26, 2020 14:19
Radiomics to predict response to immunotherapy: an imminent reality? Future Oncol. 2020 May 23;: Authors: Limkin EJ, Sun R PMID: 32447997 [PubMed - as supplied by publisher]
Tue May 26, 2020 14:19
Making precision surgical strategies a reality: are we ready for a paradigm shift in thoracic surgical oncology? Future Oncol. 2020 May 24;: Authors: Migliore M, Halezeroglu S, Mueller MR PMID: 32447984 [PubMed - as supplied by publisher]
Tue May 26, 2020 14:19
The hypothesis of internal mammary lymph node drainage chain in breast cancer. Future Oncol. 2020 May 23;: Authors: Bi Z, Chen P, Song XR, Wang YS PMID: 32447966 [PubMed - as supplied by publisher]
Tue May 26, 2020 14:19
35 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human homeostasis These pubmed results were generated on 2020/05/26PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Tue May 26, 2020 14:19
Repositioning accuracy of a novel thermoplastic mask for head and neck cancer radiotherapy. Phys Med. 2020 May 22;74:92-99 Authors: Fukao M, Okamura K, Sabu S, Akino Y, Arimura T, Inoue S, Kado R, Seo Y Abstract PURPOSE: The aim of this study was to assess the reproducibility of patient shoulder position immobilized with a novel and innovative prototype mask (E-Frame, Engineering System). METHODS: The E-frame mask fixes both shoulders and bisaxillary...
Tue May 26, 2020 14:18
Related ArticlesCritical review and quality-assessment of cost analyses in radiotherapy: How reliable are the data? Radiother Oncol. 2019 12;141:14-26 Authors: Defourny N, Monten C, Grau C, Lievens Y, Perrier L Abstract PURPOSE/OBJECTIVE: Health economic evaluations (HEE) are increasingly having an impact on policymakers, although the results greatly depend on the quality of the methodology used and on transparent reporting. The two main objectives...
Tue May 26, 2020 14:18
Publication date: Available online 25 May 2020Source: Clinical Neurology and NeurosurgeryAuthor(s): Wei Ting Chiu, Ting Yi Lee, Lung Chan, Dean Wu, Li Kai Huang, David Yen-Ting Chen, Yao Tung Lee, Chaur Jong Hu, Chien Tai Hong
Tue May 26, 2020 14:18
Publication date: Available online 25 May 2020Source: Clinical Neurology and NeurosurgeryAuthor(s): Ying Xu, Maree L. Hackett, Armin Nikpour, Ernest Somerville, Andrew Bleasel, Carol Ireland, Daniel F. Ghougassian, Craig S. Anderson, Nick Glozier
Tue May 26, 2020 14:18
Publication date: Available online 25 May 2020Source: Clinical Neurology and NeurosurgeryAuthor(s): Daisuke Ishikawa, Tokuzo Maruyama, Takumi Nakamura, Setsuki Tsukagoshi, Natsumi Furuta, Kazuaki Nagashima, Fumiaki Honda, Yoshio Ikeda
Tue May 26, 2020 14:18
Publication date: Available online 25 May 2020Source: Clinical Neurology and NeurosurgeryAuthor(s): Elife Akgun, Mehmet Yigit Akgun, Sait Sager, Ali Metin Kafadar
Tue May 26, 2020 14:18
Abstract Background Denture use for recovery of major tooth loss can reduce the need for care, and thus, it is important for dentists to identify the types of patients that use removable dentures. Objective To identify factors associated with removable denture use in independent older Japanese people. Methods This cross‐sectional study investigated the oral condition; demographics; lifestyle; dental visit behavior; and higher‐level functional capacity, as assessed using the Tokyo...
Mon May 25, 2020 11:23
Publication date: Available online 26 May 2020Source: BrachytherapyAuthor(s): Harjot Kaur Bajwa, Rohith Singareddy, Alluri Krishnam Raju
Tue May 26, 2020 14:17
Publication date: Available online 25 May 2020Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Christian Calvo-Henriquez, Robson Capasso, Carlos Chiesa-Estomba, Stanley Yung Liu, Silvia Martins-Neves, Elena Castedo, Carlos O’Connor-Reina, Alberto Ruano-Ravina, Sandra Kahn
Tue May 26, 2020 14:16
Publication date: Available online 26 May 2020Source: Medical HypothesesAuthor(s): SD Le Bon, M Horoi
Tue May 26, 2020 14:15
Publication date: Available online 26 May 2020Source: Medical HypothesesAuthor(s): Ramachandran Meenakshisundaram, Subramanian Senthilkumaran, Ponniah Thirumalaikolundusubramanian
Tue May 26, 2020 14:15
Publication date: Available online 25 May 2020Source: Medical HypothesesAuthor(s): Amit Kumar, Yuichi Kubota, Mikhail Chernov, Hidetoshi Kasuya
Tue May 26, 2020 14:15
Publication date: Available online 25 May 2020Source: Medical HypothesesAuthor(s): Sukriti Vishwas, Ankit Awasthi, Leander Corrie, Sachin Kumar Singh, Monica Gulati
Tue May 26, 2020 14:15
Publication date: Available online 26 May 2020Source: Journal of VoiceAuthor(s): Patrick O. McGarey, C. Blake Simpson, James J Daniero
Tue May 26, 2020 14:12
Alternatives to Acid Suppression Treatment for Laryngopharyngeal Reflux. Ann Otol Rhinol Laryngol. 2020 May 25;:3489420922870 Authors: Huestis MJ, Keefe KR, Kahn CI, Tracy LF, Levi JR Abstract OBJECTIVE: Laryngopharyngeal reflux (LPR) and associated symptoms can be refractory to treatment with acid suppressing medication. We investigated the role and evidence for complementary and alternative medicine (CAM) for LPR in this systematic review. ...
Tue May 26, 2020 14:10
Dysfunctional connectivity in posterior brain regions involved in cognitive control in schizophrenia: A preliminary fMRI study. J Clin Neurosci. 2020 May 21;: Authors: Barbalat G, Franck N Abstract Cognitive control, the ability to use goal-directed information to guide behaviour, is impaired in schizophrenia, and mainly related to dysfunctions within the fronto-posterior brain network. However, cognitive control is a broad cognitive function encompassing...
Tue May 26, 2020 14:09
Abstract Purpose of Review The purpose of this review is to discuss the interaction between aging, progressive disease course, disability worsening, and treatment strategies in multiple sclerosis (MS). Recent Findings The transition from the relapsing-remitting phase to the progressive phase in MS often happens in the fifth decade. In...
Tue May 26, 2020 03:00
Objectives: To explore the relationship between aural symptoms during baro-challenge and the underlying measured Eustachian tube (ET) function. Two key questions were addressed. (1) In patients who have features of obstructive ET dysfunction, is there a measurable underlying difference in ET function between those who experience severe symptoms on baro-challenge and those that do not? (2) What is the diagnostic value of ET function tests in the identification of patients with severe symptoms on baro-challenge?...
Tue May 26, 2020 12:09
Publication date: Available online 25 May 2020Source: Cancer/RadiothérapieAuthor(s): T. Felefly, S. Achkar, N. Khater, R. Sayah, G. Fares, N. Farah, J. El Barouky, F. Azoury, C. El Khoury, C. Roukoz, D. Nehme Nasr, E. Nasr
Tue May 26, 2020 13:54
Potential Markers of Dietary Glycemic Exposures for Sustained Dietary Interventions in Populations without Diabetes. Adv Nutr. 2020 May 25;: Authors: Feskens E, Brennan L, Dussort P, Flourakis M, Lindner LME, Mela D, Rabbani N, Rathmann W, Respondek F, Stehouwer C, Theis S, Thornalley P, Vinoy S Abstract There is considerable interest in dietary and other approaches to maintaining blood glucose concentrations within the normal range and minimizing exposure...
Tue May 26, 2020 13:51
Dietary Sodium Intake and Health Indicators: A Systematic Review of Published Literature between January 2015 and December 2019. Adv Nutr. 2020 May 25;: Authors: Overwyk KJ, Quader ZS, Maalouf J, Bates M, Webster J, George MG, Merritt RK, Cogswell ME Abstract As the science surrounding population sodium reduction evolves, monitoring and evaluating new studies on intake and health can help increase our understanding of the associated benefits and risks....
Tue May 26, 2020 13:51
Microplot Design and Plant and Soil Sample Preparation for 15Nitrogen Analysis. J Vis Exp. 2020 May 10;(159): Authors: Spackman JA, Fernandez FG Abstract Many nitrogen fertilizer studies evaluate the overall effect of a treatment on end-of-season measurements such as grain yield or cumulative N losses. A stable isotope approach is necessary to follow and quantify the fate of fertilizer derived N (FDN) through the soil-crop system. The purpose of...
Tue May 26, 2020 13:51
Isolation of Human Ventricular Cardiomyocytes from Vibratome-Cut Myocardial Slices. J Vis Exp. 2020 May 10;(159): Authors: Fiegle DJ, Volk T, Seidel T Abstract The isolation of ventricular cardiac myocytes from animal and human hearts is a fundamental method in cardiac research. Animal cardiomyocytes are commonly isolated by coronary perfusion with digestive enzymes. However, isolating human cardiomyocytes is challenging because human myocardial...
Tue May 26, 2020 13:51
Potato Virus X-Based microRNA Silencing (VbMS) In Potato. J Vis Exp. 2020 May 11;(159): Authors: Zhao J, Rios CG, Song J Abstract Virus-based microRNA silencing (VbMS) is a rapid and efficient tool for functional characterization of microRNAs (miRNAs) in plants. The VbMS system has been developed and applied for various plant species including Nicotiana benthamiana, tomato, Arabidopsis, cotton, and monocot plants such as wheat and maize. Here, we...
Tue May 26, 2020 13:51
Cryogenic Liquid Jets for High Repetition Rate Discovery Science. J Vis Exp. 2020 May 09;(159): Authors: Curry CB, Schoenwaelder C, Goede S, Kim JB, Rehwald M, Treffert F, Zeil K, Glenzer SH, Gauthier M Abstract This protocol presents a detailed procedure for the operation of continuous, micron-sized cryogenic cylindrical and planar liquid jets. When operated as described here, the jet exhibits high laminarity and stability for centimeters. Successful...
Tue May 26, 2020 13:51
In Vitro ELISA Test to Evaluate Rabies Vaccine Potency. J Vis Exp. 2020 May 11;(159): Authors: Jallet C, Tordo N Abstract The growing global concern for the animal welfare is encouraging manufacturers and the National Control Laboratories (OMCLs) to follow the 3Rs strategy for the Replacement, Reduction, and Refinement of the laboratory animal testing. The development of in vitro approaches is recommended at the WHO and European levels as alternatives...
Tue May 26, 2020 13:51
Exon Skipping in Directly Reprogrammed Myotubes Obtained from Human Urine-Derived Cells. J Vis Exp. 2020 May 07;(159): Authors: Takizawa H, Sato M, Aoki Y Abstract Duchenne muscular dystrophy (DMD), a progressive and fatal muscle disease, is caused by mutations in the DMD gene that result in the absence of dystrophin protein. To date, we have completed an investigator-initiated first-in-human study at the National Center of Neurology and Psychiatry...
Tue May 26, 2020 13:51
Parallel High Throughput Single Molecule Kinetic Assay for Site-Specific DNA Cleavage. J Vis Exp. 2020 May 06;(159): Authors: Matozel EK, Dale N, Price AC Abstract Site-specific DNA cleavage (SSDC) is a key step in many cellular processes, and it is crucial to gene editing. This work describes a kinetic assay capable of measuring SSDC in many single DNA molecules simultaneously. Bead-tethered substrate DNAs, each containing a single copy of the target...
Tue May 26, 2020 13:51
Model of Ischemic Heart Disease and Video-Based Comparison of Cardiomyocyte Contraction Using hiPSC-Derived Cardiomyocytes. J Vis Exp. 2020 May 05;(159): Authors: Liu Y, Liang Y, Wang M, Wang C, Wei H, Naruse K, Takahashi K Abstract Ischemic heart disease is a significant cause of death worldwide. It has therefore been the subject of a tremendous amount of research, often with small-animal models such as rodents. However, the physiology of the human...
Tue May 26, 2020 13:51
Studying Effects of Cigarette Smoke on Pseudomonas Infection in Lung Epithelial Cells. J Vis Exp. 2020 May 11;(159): Authors: Li T, Long C, Fanning KV, Zou C Abstract Cigarette smoking is the major etiological cause for lung emphysema and chronic obstructive pulmonary disease (COPD). Cigarette smoking also promotes susceptibility to bacterial infections in the respiratory system. However, the effects of cigarette smoking on bacterial infections in...
Tue May 26, 2020 13:51
Detection of Vascular Pathways of Oral Mucosa Influencing Soft- and Hard Tissue Surgeries by Latex Milk Injection. J Vis Exp. 2020 May 07;(159): Authors: Shahbazi A, Pilsl U, Molnár B, Feigl G Abstract In this methodological study, the purpose was to visualize the macroscopic vascular pathway of the oral mucosa. Corpses were injected and fixed with Thiel's solution for embalming to keep the natural color, fresh texture, and elasticity of the tissues....
Tue May 26, 2020 13:51
In Vivo Targeting of Xenografted Human Cancer Cells with Functionalized Fluorescent Silica Nanoparticles in Zebrafish. J Vis Exp. 2020 May 08;(159): Authors: Qin X, Laroche FFJ, Peerzade SAMA, Lam A, Sokolov I, Feng H Abstract Developing nanoparticles capable of detecting, targeting, and destroying cancer cells is of great interest in the field of nanomedicine. In vivo animal models are required for bridging the nanotechnology to its biomedical application....
Tue May 26, 2020 13:51
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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,