Dearomatization of 3‐Nitroindoles via a Phosphine‐catalyzed Enantioselective [3+2] Annulation Reaction

A dearomatization process of 3‐nitroindoles via a chiral phosphine‐mediated [3+2] annulation reaction has been developed. This method makes use of readily available 3‐nitroindoles as an aromatic feedstock and quickly delivers a wide range of cyclopentaindoline alkaloid scaffolds in a highly enantioselective manner. Notably, this is the first time that phosphine‐triggered cyclization has been utilized in a dearomatization process.

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