TP53LNC-DB, the database of lncRNAs in the p53 signalling network.

TP53LNC-DB, the database of lncRNAs in the p53 signalling network.

Database (Oxford). 2019 Jan 01;2019:

Authors: Khan MR, Bukhari I, Khan R, Hussain HMJ, Wu M, Thorne RF, Li J, Liu G

Abstract
The TP53 gene product, p53, is a pleiotropic transcription factor induced by stress, which functions to promote cell cycle arrest, apoptosis and senescence. Genome-wide profiling has revealed an extensive system of long noncoding RNAs (lncRNAs) that is integral to the p53 signalling network. As a research tool, we implemented a public access database called TP53LNC-DB that annotates currently available information relating lncRNAs to p53 signalling in humans.

PMID: 30624647 [PubMed - in process]

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