Promoter-proximal pausing mediated by the exon junction complex regulates splicing

Promoter-proximal pausing mediated by the exon junction complex regulates splicing

Promoter-proximal pausing mediated by the exon junction complex regulates splicing, Published online: 31 January 2019; doi:10.1038/s41467-019-08381-0

The exon junction complex (EJC) has been identified as functioning as a post-transcriptional gene regulator. Here the authors reveal that the complex also plays a part in the regulation of transcription by regulating the release of Pol II pausing into transcription elongation.

from A via a.sfakia on Inoreader https://go.nature.com/2RsDVZM