Post-exposure immunotherapy for two ebolaviruses and Marburg virus in nonhuman primates

Post-exposure immunotherapy for two ebolaviruses and Marburg virus in nonhuman primates

Post-exposure immunotherapy for two ebolaviruses and Marburg virus in nonhuman primates, Published online: 10 January 2019; doi:10.1038/s41467-018-08040-w

Current experimental monoclonal antibodies (mAbs) for Ebola virus (EBOV) post-exposure immunotherapy are ineffective against Sudan (SUDV) or Marburg virus (MARV). Here, authors develop cocktails of mAbs that protect nonhuman primates against EBOV, SUDV, and MARV infection when given four days post infection.

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