Olefin-accelerated solid-state C–N cross-coupling reactions using mechanochemistry

Olefin-accelerated solid-state C–N cross-coupling reactions using mechanochemistry

Olefin-accelerated solid-state C–N cross-coupling reactions using mechanochemistry, Published online: 10 January 2019; doi:10.1038/s41467-018-08017-9

Cross-coupling reactions have been achieved in solution, yet tend to be inefficient in a solid state. Here, the authors report a solid-state palladium-catalyzed Buchwald-Hartwig cross-coupling using olefins as molecular dispersants, enabling reduction of solvent waste.

from A via a.sfakia on Inoreader https://go.nature.com/2M4bxMn