Extracranial-intracranial bypass for cerebral vasculitis after graft-versus-host disease: case report and literature review.

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Extracranial-intracranial bypass for cerebral vasculitis after graft-versus-host disease: case report and literature review.

World Neurosurg. 2018 Dec 18;:

Authors: Nakayama Y, Kamio Y, Kato N, Murayama Y

Abstract
BACKGROUND: Cerebral vasculitis due to chronic graft-versus-host disease (GVHD) is very rare. To our knowledge, two cases have been reported. We describe the first case of superficial temporal artery-middle cerebral artery (STA-MCA) bypass for cerebral vasculitis due to GVHD.
CASE DESCRIPTION: A 59-year-old female presented with right upper extremity weakness and dysarthria 33 months after undergoing matching allogenic bone marrow transplantation (BMT). The patient had STA-MCA bypass for middle cerebral artery occlusion and resting cerebral blood flow in the left MCA area improved.
CONCLUSION: Although the mechanism of cerebral vasculitis after chronic GVHD is not known, cerebral vasculitis that causes cerebrovascular disease long after BMT should be considered. In this case, an STA-MCA bypass was efficient for the repeated ischemic attacks due to cerebral vasculitis. Moreover, it is important to select the optimal recipient vessels to area originated neurological symptoms.

PMID: 30576821 [PubMed - as supplied by publisher]

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