Source:Diagnostic Microbiology and Infectious Disease
Author(s): Vidthiya Menon, Rebecca Davis, Nick Shackel, Bjorn A. Espedido, Alicia G. Beukers, Slade O. Jensen, Sebastiaan J. van Hal
Daptomycin β-Lactam combination therapy offers "protection" against daptomycin non-susceptibility (DNS) development in Enterococcus faecium. We report failure of this strategy and the importance of source control. Mutations were detected in the LiaF and cls genes in DNS isolates. A single DNS isolate contained an unrecognized mutation, which requires confirmation.
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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,