Evaluation of the diagnostic efficacy and spectrum of autofluorescence of benign, dysplastic and malignant lesions of the oral cavity using VELscope

In individuals exposed to risk factors; the prevention and early detection of oral cancer play a significant role in increasing the survival rates [1,2]. In the absence of a definitive approach, screening of oral cancer is still largely based on conventional oral examination (COE) and scalpel biopsy in case of suspicious lesions [3,4]. Since visible changes in the oral mucosa are known to precede the development of virtually all oral squamous cell carcinomas (OSCCs), various adjunctive techniques have been introduced with the aim to assist in the detection of early cancerous mucosal changes that can be occult to visual inspection [5,6].

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