Electronic medical records can be used to emulate target trials of sustained treatment strategies

To emulate three target trials: single treatment versus no treatment, joint treatment versus no treatment, and head-to-head comparison of two treatments. We explain how to estimate the observational analogs of intention-to-treat and per-protocol effects, using hazard ratios and survival curves. For per-protocol effects, we describe two methods for adherence adjustment via inverse-probability weighting.

from ! ORL Sfakianakis via paythelady.61 on Inoreader http://ift.tt/2zVGAHt
via IFTTT