Functional disability and other health-related quality-of-life domains: points to consider for clinical trials in systemic sclerosis.

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Functional disability and other health-related quality-of-life domains: points to consider for clinical trials in systemic sclerosis.

Rheumatology (Oxford). 2017 Sep 01;56(suppl_5):v17-v22

Authors: Khanna D, Hays RD, Furst DE

Abstract
Patients with SSc have the highest mortality among the rheumatic diseases. In addition, SSc is associated with disfigurement, hand contractures, fatigue, poor sleep, severe RP with numbness and tingling of the fingers can lead to decrements in quality of life. This Points to Consider article provides practical considerations for design of trials for functional disability and other health-related quality-of-life issues.

PMID: 28992164 [PubMed - indexed for MEDLINE]

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