Keeping the Rhythm while Changing the Lyrics: Circadian Biology in Aging

Publication date: 10 August 2017
Source:Cell, Volume 170, Issue 4
Author(s): Fumiyuki Hatanaka, Alejandro Ocampo, Juan Carlos Izpisua Belmonte
Aging and circadian rhythms have been linked for decades, but their molecular interplay has remained obscure. Sato et al. and Solanas et al. now reveal that, while core clock components remain nearly unaltered, aging is associated with tissue-specific rewiring, which can be prevented by calorie restriction.

Teaser

Aging and circadian rhythms have been linked for decades, but their molecular interplay has remained obscure. Sato et al. and Solanas et al. now reveal that, while core clock components remain nearly unaltered, aging is associated with tissue-specific rewiring, which can be prevented by calorie restriction.


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