Brain Sciences, Vol. 7, Pages 106: A Review of the Neuropsychological Dimensions of Tourette Syndrome

Brain Sciences, Vol. 7, Pages 106: A Review of the Neuropsychological Dimensions of Tourette Syndrome

Brain Sciences doi: 10.3390/brainsci7080106

Authors: Simon Morand-Beaulieu Julie Leclerc Philippe Valois Marc Lavoie Kieron O'Connor Bruno Gauthier

Neurocognitive functioning in Tourette syndrome (TS) has been the subject of intensive research in the past 30 years. A variety of impairments, presumably related to frontal and frontostriatal dysfunctions, have been observed. These impairments were found in various domains, such as attention, memory, executive functions, language, motor and visuomotor functions, among others. In line with contemporary research, other neurocognitive domains have recently been explored in TS, bringing evidence of altered social reasoning, for instance. Therefore, the aims of this review are to give an overview of the neuropsychological dimensions of TS, to report how neuropsychological functions evolve from childhood to adulthood, and to explain how various confounding factors can affect TS patients' performance in neuropsychological tasks. Finally, an important contribution of this review is to show how recent research has confirmed or changed our beliefs about neuropsychological functioning in TS.

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