A Viro-Immunotherapy Triple Play for the Treatment of Glioblastoma

Publication date: 14 August 2017
Source:Cancer Cell, Volume 32, Issue 2
Author(s): John C. Bell, Carolina S. Ilkow
In this issue of Cancer Cell, Saha et al. systematically test and optimize combination therapy strategies in a challenging model of glioblastoma. Durable complete responses were seen only when an oncolytic virus expressing IL12 was coupled with anti-CTLA-4 and anti-PD-1 therapeutics.

Teaser

In this issue of Cancer Cell, Saha et al. systematically test and optimize combination therapy strategies in a challenging model of glioblastoma. Durable complete responses were seen only when an oncolytic virus expressing IL12 was coupled with anti-CTLA-4 and anti-PD-1 therapeutics.


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