Quality of life and psychological disturbances in adults with atopic dermatitis in the Czech Republic.

Quality of life and psychological disturbances in adults with atopic dermatitis in the Czech Republic.

J Biol Regul Homeost Agents. 2017 07 13;31(2 Suppl. 2)

Authors: Březinová E, Nečas M, Vašků V

Abstract
Atopic dermatitis (AD) leads to severe psychosocial disturbances that are quite frequently underestimated. We evaluate the quality of life (QoL) of adult patients with AD and their family members using DLQI, B-IPQ, FDLQI questionnaires, observe psychopathological features with CAQ II questionnaire and evaluate correlations between QoL, psychological disturbances and objective/subjective parameters of disease severity. A reduction in QoL has been proven by all questionnaires with statistically significant relationships between all of them. The QoL of the patient (DLQI, B-IPQ) was found to be correlated to FDLQI. We also confirmed statistically significant relationships between DLQI, FDLQI, B-IPQ and objective severity of AD, as evaluated by SCORAD, in DLQI and FDLQI also by TEWL, in B-IPQ also by IgE. All the QoL questionnaires have statistically significant relationship to subjective symptoms (pruritus and sleep disturbance). Interestingly, no significant relationship between QoL and age and extent of eczema in visible localizations was found. CAQ II revealed high numbers of psychological disturbances - the most often paranoia, hypochondria, suicidal depression, anxiety and depression - and high prevalence of suicidal thoughts (10.9%). Although AD is not life-threatening, its negative impact on the QoL of adult patients and their family members/partners can be further influenced by pathological personality traits of the patients.

PMID: 28702987 [PubMed - as supplied by publisher]

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