Letter to the Editor regarding: Rat model of chronic tympanic membrane perforation: Ventilation tube with mitomycin C and dexamethasone

We would like to address the manuscript titled "Rat model of chronic tympanic membrane perforation: Ventilation tube with mitomycin C and dexamethasone" by Wang et al.1 This is an interesting study. The creation of an ideal animal model of chronic tympanic membrane perforation (TMP) will be of great importance in the development of biological graft materials for myringoplasty. However, we believe that the technique used by Wang et al. is not reliable, and it is also different from human chronic TMP with chronic suppurative otitis media (CSOM).

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