Hydroxychloroquine and risk of cancer in patients with primary Sj ögren syndrome: propensity score matched landmark analysis.

Hydroxychloroquine and risk of cancer in patients with primary Sjögren syndrome: propensity score matched landmark analysis. Oncotarget. 2017 Jul 06;: Authors: Fang YF, Chen YF, Chung TT, See LC, Yu KH, Luo SF, Kuo CF, Lai JH Abstract Hydroxychloroquine inhibits systemic inflammation and autophagy and may thus have antineoplastic effects [1]. We investigated the effect of hydroxychloroquine on cancer risk in patients with primary Sjögren syndrome(pSS). We used the Taiwan National Health Insurance Database to compare cancer incidence between incident pSS patients with or without at least 6-month hydroxychloroquine use within a 1- or 3-year period. Propensity score matched landmark analysis was used. We included 4194 alive patients without cancer 1 year after pSS diagn...

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