Lack of the liver-specific microRNA-122 spontaneously results in hepatocellular carcinoma in mice. Luna et al. provide a comprehensive and biochemically defined catalog of miR-122 targets in mice and humans to uncover novel features of miR-122 targeting that may offer predictive value for human HCC survival. (Source: Molecular Cell)
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Πέμπτη 20 Ιουλίου 2017
Argonaute CLIP Defines a Deregulated miR-122-Bound Transcriptome that Correlates with Patient Survival in Human Liver Cancer
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