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Σάββατο 17 Ιουνίου 2017

Vincristine ‐induced neuropathy in pediatric patients with acute lymphoblastic leukemia in Oman: Frequent autonomic and more severe cranial nerve involvement

ConclusionsPeripheral neuropathy was the commonest form of VCR‐related neuropathy. Autonomic neuropathy was relatively common in our patients. Cranial neuropathy is a serious side effect of VCR that can be severe, involving multiple cranial nerves and needs prompt recognition and management. Concomitant administration of pyridoxine and pyridostigmine does not seem to protect against further neurological damage in some patients. (Source: Pediatric Blood and Cancer)

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