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Perturbations or "dysbiosis" of the bronchial microbiota have been implicated in the pathogenesis of asthma. However, it remains unclear whether reported differences are reflective of atopy, a common comorbidity of asthma. In a National Heart, Lung, and Blood Institute AsthmaNet study of well-characterized adults with mild, atopic, inhaled corticosteroid–naive asthma, Durack et al (p 63) describe the following key findings:

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