Impact of physiological breathing motion for breast cancer radiotherapy with proton beam scanning – An in silico study

The favourable potential of protons resulting from finite range and practically zero dose deposition beyond the Bragg peak has made this radiation modality an interesting candidate to reduce the radiation burden and hence the risk of complications from radiation therapy. This is quite relevant for breast cancer patients where radiotherapy has been shown to improve local control and overall survival [1], increasing the concern for late cardiopulmonary toxicity in long-term survivors. Several studies have investigated the potential of scanned proton beams for breast radiation therapy showing that the technique could increase target conformity and thus reduce doses to the normal tissues of interest [2 –6]. (Source: Physica Medica: European Journal of Medical Physics)

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