[A Case of HER2 Positive Locally Advanced Breast Cancer Successfully Treated with a Combination Therapy of Eribulin, Trastuzumab and Pertuzumab].

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[A Case of HER2 Positive Locally Advanced Breast Cancer Successfully Treated with a Combination Therapy of Eribulin, Trastuzumab and Pertuzumab].

Gan To Kagaku Ryoho. 2018 Dec;45(13):2470-2472

Authors: Sazuka T, Kimura M, Kamata T, Isozaki T, Urahama R, Tasaki K, Sugamoto Y, Watanabe Y, Asai Y, Fukunaga T, Matsubara H

Abstract
The patient was an 82-year-oldwoman. She consultedour hospital with a chief complaint of left breast mass. MRI showed enhancedtumor with skin andextensive pectoral muscle invasion, so it was unresectable. Immunohistopathological analysis revealeda HER2-positive lesion. We administerederibulin, trastuzumab andpertuzumab, after which the tumor became resectable. Histological examination revealedremarkable response. Combination therapy of eribulin, trastuzumab andpertuzumab was well toleratedandconsid eredto be effective.

PMID: 30692501 [PubMed - in process]

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