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Σάββατο 8 Ιουλίου 2017

Retinoic Acid Puts Hematopoietic Stem Cells Back To Sleep.

Retinoic Acid Puts Hematopoietic Stem Cells Back To Sleep.

Cell Stem Cell. 2017 Jul 06;21(1):9-11

Authors: Rundberg Nilsson A, Pronk CJ

Abstract
Dormant hematopoietic stem cells (dHSCs) display superior serial reconstitution capacity compared to active HSCs, although their role in normal hematopoiesis has not been thoroughly investigated. Recently in Cell, Cabezas-Wallscheid et al. (2017) demonstrate involvement of retinoic acid signaling in murine dHSCs for preservation of the HSC pool.

PMID: 28686871 [PubMed - in process]



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