18F-Fluorocholine is a relatively new, extremely versatile radiotracer for detecting proliferative or mitogenic activity. Its diagnostic potential has been explored in cancers of the prostate, liver, esophagus, breast, brain, and lung, as well as lymphoma, sarcoma, melanoma, and parathyroid adenomas. The authors present a case where fluorocholine PET/CT performed for characterizing a space-occupying lesion in the brain revealed intensely tracer-avid skull lesions with intracranial soft tissue component and multiple other skeletal lesions. Fine-needle aspiration cytology from the skull and chest wall lesions confirmed the diagnosis of plasma cell neoplasm. Received for publication July 27, 2018; revision accepted October 25, 2018. Conflicts of interest and sources of funding: none declared. Correspondence to: Anish Bhattacharya, DNB, PhD, Department of Nuclear Medicine, 'A' Block, Ground floor, Nehru Hospital, PGIMER, Sector 12, Chandigarh 160012, India. E-mail: anishpgi@yahoo.co.in. Copyright © 2018 Wolters Kluwer Health, Inc. All rights reserved.
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