Πέμπτη 7 Δεκεμβρίου 2017

[Correspondence] Antiplatelet cessation to manage bleeding events in elderly people

In their Article in The Lancet, Linxin Li and colleagues (June 13, p 490)1 postulated that the increased risk of bleeding events with antiplatelet therapy in patients older than 75 years is sufficient to routinely prescribe proton-pump inhibitors (PPIs) in this group. This assumption is based on extrapolation from data showing the efficacy of PPIs in prevention of upper gastrointestinal bleeding in a younger population (mean age 68·4 years).2 What the authors do not consider is the opposite solution: cessation of antiplatelet therapy.

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