We agree with Cody Magnusson that little evidence exists to suggest that long-term use of aspirin in primary prevention of vascular events is effective in people older than 70 years. Indeed, we previously suggested that aspirin might be used for primary prevention of vascular events and cancer in people who are middle-aged,1,2 but should then be gradually withdrawn because of the high risk of bleeding at older ages. We await the results of the ASPREE trial,3 which should provide definitive evidence of the short-term benefits and harms of aspirin use in people older than 70 years.
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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,