The Utility of Liquid-Biopsy by Improved PNA-LNA PCR Clamp Method for Detecting EGFR Mutation at The Initial Diagnosis of NSCLC: AN Observational Study of 190 Consecutive Cases in Clinical Practice.

We reviewed 190 consecutive, unselected patients who received a liquid-biopsy for detecting an EGFR mutation. The results indicated that not all patients should be candidates for liquid-biopsy at initial diagnosis, while some patients gain benefit from initial liquid-biopsy in clinical practice. This real-world data would supply useful information in discussing appropriate patients for liquid-biopsy.

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