Role of Mesenchymal Stem Cells in Cancer Development and Their Use in Cancer Therapy.

Authors: Serakinci N, Tulay P, Kalkan R Abstract Stem cells have the ability to perpetuate themselves through self-renewal and generate mature cells of a particular tissue through differentiation. Mesenchymal stem cells (MSCs) play an important role in tissue homeostasis - supporting tissue regeneration. MSCs are rare pluripotent cells supporting hematopoietic and mesenchymal cell lineages. MSCs have a great therapeutic potential in cancer therapy, as well as stem cell exosome and/or microvesicle-mediated tissue regeneration. In this review, the use of hMSCs in stem cell-mediated cancer therapy is discussed. PMID: 28730382 [PubMed - as supplied by publisher] (Source: Advances in Experimental Medicine and Biology)

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