Regulatory T-cell populations in children are affected by age and food allergy diagnosis

The prevalence of food allergy continues to increase, and although there is evidence that early food introduction may be beneficial, the immunologic mechanisms predisposing an individual to develop food allergy remain elusive.1 In addition, early atopic disease is a risk factor for the development of asthma, a progression termed the atopic march.1,2 Regulatory T (Treg) cells play an important role in maintaining self-tolerance, and oral immunotherapy studies have shown that increases in CD4+CD25+Foxp3+ cells are associated with clinical efficacy. (Source: Journal of Allergy and Clinical Immunology)

from ! Medicine by Alexandros G. Sfakianakis via alwin on Inoreader http://ift.tt/2sTfCvw
via IFTTT