Evaluation of Effect of Foraminal Enlargement of Necrotic Teeth on Postoperative Symptoms: A Systematic Review and Meta-analysis

The intentional enlargement of the apical foramen is designed to reduce the microbial load in the apical foramen, or even beyond, to levels more favorable for repair. This study provides a systematic review and meta-analysis to address the PICOS question: in adult patients who undergo endodontic treatment, does foraminal enlargement (FE) cause different postoperative symptoms in comparison with conventional endodontic treatment?

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