Comparison of Single- and Three-Fraction Schedules of Stereotactic Body Radiation Therapy for Peripheral Early-Stage Non-Small Cell Lung Cancer

We compared the clinical outcome of single- and three-fraction stereotactic body radiation therapy schedules for early-stage non-small cell lung cancer (n=159). No statistical difference in clinical outcomes between these two regimens was observed, despite the single-fraction group that included more patients with worse performance status. This suggests a single-fraction regimen is a reasonable option.

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