Mechanisms of Ototoxicity and Otoprotection

xlomafota13 shared this article with you from Inoreader Mechanisms of Ototoxicity and Otoprotection Via Otolaryngologic Clinics of North America Ototoxicity refers to damage to the inner ear that leads to functional hearing loss or vestibular disorders by selected pharmacotherapeutics as well as a variety of environmental exposures (eg, lead, cadmium, solvents). This article reviews the fundamental mechanisms underlying ototoxicity by clinically relevant, hospital-prescribed medications (ie, aminoglycoside antibiotics or cisplatin, as illustrative examples). Also reviewed are current strategies to prevent prescribed medication-induced ototoxicity, with several clinical or candidate interventional strategies being discussed. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.