Role of the Prognostic Nutritional Index in Patients With Soft-tissue Sarcoma

xlomafota13 shared this article with you from Inoreader Role of the Prognostic Nutritional Index in Patients With Soft-tissue Sarcoma Via In vivo (Athens, Greece) In Vivo. 2021 Jul-Aug;35(4):2349-2355. doi: 10.21873/invivo.12511. ABSTRACT BACKGROUND: This study aimed to determine whether the prognostic nutritional index (PNI) can predict the prognosis in patients with soft-tissue sarcoma (STS) before treatment and to examine whether there is an association between PNI values and clinical characteristics. PATIENTS AND METHODS: The data on 100 patients with primary STS were retrospectively reviewed. The cohort included 55 men and 45 women, with a mean age of 64 years. The mean follow-up duration was 41.7 months. RESULTS: The median PNI was 51.35. The PNI was significantly inversely associated with tumor size, tumor grade, and age. We found that the PNI was a significant prognostic marker for disease-specific and event-free survival using univariate and multivariate analyses. Patients with a low PNI had poorer disease-specific and event-free survival than those with a high PNI. CO NCLUSION: These results suggest that the PNI can be used as a prognostic marker in patients with STS. PMID:34182517 | DOI:10.21873/invivo.12511 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.