Two dichloric compounds inhibit in vivo U87 xenograft tumor growth.

Related ArticlesTwo dichloric compounds inhibit in vivo U87 xenograft tumor growth. Cancer Biol Ther. 2019 Jun 24;:1-9 Authors: Ovcharenko D, Chitjian C, Kashkin A, Fanelli A, Ovcharenko V Abstract Dichloroacetate (DCA) is an inhibitor of pyruvate dehydrogenase kinase (PDK) that has been shown to reverse the Warburg effect and cause tumor cell death. Clinical research into the anti-cancer activity of DCA revealed high dosage requirements and reports...

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Thu Jun 27, 2019 14:13