The Fear of Fat

The link between cellular senescence and the pro-inflammatory signaling networks that contribute to aging and age-related diseases is well established (1). But what drives the link between senescence and neuropsychiatric disorders, such as obesity-induced anxiety – a common condition with serious implications that range from social isolation to suicidal ideation? To find out more, a multinational team of researchers induced obesity in mouse models using a high-fat diet feeding regimen (2)....

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