Long-term treatment outcomes and prognosis of mucosal melanoma of the head and neck: 161 cases from a single institution

Mucosal melanoma is a rare malignant neoplasm, accounting for only 0.8–3.7% of all melanomas [1,2]. The most common site of mucosal melanoma is the upper aerodigestive tract, which accounts for 55% of all cases [1]. Several studies have reported that MMHN is more common in some parts of African countries and Japan than in Western countries [3,4]. The most common primary sites of MMHN are the sinonasal cavity and oral cavity. Although rare, MMHN is a very aggressive malignancy, with 5-year OS ranges from 20% to 40% [5–8].

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