Peri-Implant Osteogenesis Behavior in Ovariectomized Rats Treated with Strontium Ranelate

The aim of this study was to evaluate the bone repair and biomechanical responss after installation of implants in tibia of ovariectomized rats treated with strontium ranelate (RE). 30 Wistar adult rats were divided into 3 groups (n = 10): Group OVX, rats submitted to bilateral ovariectomy; SHAM group, rats sham submitted surgery of ovariectomy; OVX group RE, rats submitted to ovariectomy and treated with RE. 30 days after ovariectomy, RE OVX rats were orally gavage 625 mg / kg / day of RE until euthanasia of the animals.

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