Oropharyngeal lymphoma: A US population based analysis

Head and neck lymphomas arise from lymph nodes as well as extranodal locations including, Waldeyer ring, the sinonasal tract, nasopharynx and salivary glands [1]. The oropharynx contains the palatine tonsils as well as the base of tongue (BOT), both of these locations are part of Waldeyer's ring and are comprised of lymphoid tissue [2]. B cells proliferate and mature at these locations, which represent the first contact point for exogenous antigens entering the aerodigestive tract [3]. Lymphomas are subdivided into Hodgkin's lymphoma (HL) and Non-Hodgkin's lymphoma (NHL), with extranodal NHL being the second most common primary head and neck malignancy after squamous cell carcinoma [4].

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