Epigenetic therapy regulates the expression of ALDH1 and immunologic response: Relevance to the prognosis of oral cancer

Oral squamous cell carcinoma (OSCC) is the most malignant tumor of the head and neck [1]. Despite considerable advances in treatment, about 50% of patients with locally advanced disease relapse with local or distant disease progression [2,3]. Investigating specific molecular markers related to the capacity for tumor invasion and treatment sensitivity could provide new insights for the identification of innovative treatments.

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