Chapter 9. Long Term Outcomes and Management of the Heart Transplant Recipient

Publication date: Available online 23 June 2017 Source:Best Practice & Research Clinical Anaesthesiology Author(s): Sharon L. McCartney, Chetan Patel, J. Mauricio Del Rio Cardiac transplantation remains the gold standard in the treatment of advanced heart failure. With advances in immunosuppression, long-term outcomes continue to improve despite older and higher-risk recipients. The median survival after heart transplantation in the adult is now 10.7 years. While early graft failure and multi-organ system dysfunction are the most important causes of early mortality; malignancy, rejection, infection, and cardiac allograft vasculopathy contribute to late mortality. Chronic renal dysfunction is common after heart transplantation and occurs in up to 68% of patients by year 10, with 6....

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